Carboprost - Drug Information

atest prescription information about Carboprost. Learn how to pronounce the drug's name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.

Therapeutic Classification : Endocrine and Metabolic Agents

Trade Name(s): 

India : 

Prostodin (1 ml) | Coboprost 125 | Prostospan (0.5ml) | Caboprost | Deviprost | Prostodin | Prostospan (1ml)

International : 

Hemabate

Why it is prescribed (Indications) : 

This medication is a synthetic prostaglandin analogue, prescribed for termination of pregnancy and also used for postpartum hemorrhage.  It induces uterine muscle contractions and can trigger abortion in early pregnancy. 

When it is not to be taken (Contraindications): 

Contraindicated in patients with pelvic inflammatory disease, heart, lung, liver or kidney disease, hypersensitivity.

Pregnancy Category :

A B C D X

Category C :

Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.

Dosage & When it is to be taken : 

Adult: IM Pregnancy termination in the 2nd trimester 250 mcg, repeat at 1.5-3.5-hrly depending on response. Max: 12 mg. Postpartum hemorrhage 250 mcg at 15-90 min intervals.

How it should be taken : 

It comes as a solution for injection to be administered by a healthcare provider. 

Warnings and Precautions : 

Caution should be exercised in patients with history of heart /lung disorders, increased eye pressure, asthma, epilepsy, severe liver or kidney dysfunction, high/low blood pressure, diabetes, during pregnancy and lactation.
It may cause dizziness or drowsiness, do not drive a car or operate machinery while taking this medication.

Side Effects : 

  Most Common- Nausea, vomiting, diarrhea and excessive uterine bleeding.

  Less Common- Abdominal pain, flushing, shivering, headache, dizziness, hypotension, fever/chills, difficulty in breathing and lung swelling.

Other Precautions : 

Take full course of treatment. 

Storage Conditions : 

Intramuscular: Refrigerate at 2-8°C.